Rated 4.8 (2,839)

Happy Customers

PureRoot Labs L-Methylfolate


Restore mood, mental clarity, and daily energy — feel brighter, calmer, and more focused from within.

  • Supports calm emotional balance
  • Improves daily focus + clarity
  • Boosts clean natural energy
  • Fast-absorbing active 5-MTHF form
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That's how confident we are in your results. But if you're not thrilled, send it back and we'll refund your purchase.

Description +

This sublingual liquid blend combines L-Methylfolate (the active 5-MTHF form) with Methyl B12 to support healthy mood, cognitive clarity, balanced methylation, and natural daily energy — in a fast-absorbing berry flavor formula.

What makes this supplement different? +

Unlike standard folic acid or cheaper folate forms, this uses bioactive 5-MTHF + Methyl B12 — the forms your body can use immediately. No conversion needed, better absorption, supports neurotransmitter balance, and is ideal for those with methylation challenges.

How long before I see full results? +

Most users begin noticing subtle improvements within 1–3 weeks. Full benefits are typically experienced with consistent daily use over 6–8 weeks as nutrient levels build and methylation support becomes more stable.

Why do I need it? +

Many people struggle to properly convert folic acid — which can impact mood, focus, energy, and methylation. This provides the active form directly, helping support healthy neurotransmitter production and daily mental performance.

Our Guarantee +

We stand behind our formula. If you don’t feel the difference within 30 days, you’re covered by our Risk-Free Satisfaction Guarantee—just reach out and we’ll make it right.

Recommended Use +

Take your daily serving under the tongue, hold briefly, then swallow. Best taken consistently each day. Follow serving size guidelines on the label or as directed by your healthcare professional.

Dr. Susan Whitaker
Dr. Susan Whitaker

I’ve recommended this formula to patients who needed support for mood + mental clarity, and many of them told me they felt a noticeable difference within a few weeks. The active forms of folate and B12 absorb really well, and that’s why I like this one.

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What Our Customers Are Saying...

Very good 4.8/5 based on 2,839 reviews

Daily Clarity, Made Simple

You don’t need stimulants, complicated stacks, or trial-and-error supplements to feel mentally centered every day. This active 5-MTHF + Methyl B12 formula supports healthy neurotransmitter balance — helping you stay calmer, think clearer, and feel more grounded naturally.

Every serving delivers fast-absorbing nutrients that support attention, mood steadiness, and day-to-day mental clarity — so you can show up sharper and more regulated, without the crash.

  • Easy to Take
  • Safe for Daily Use
  • Science-Supported
  • Natural Ingredients
  • Vegan & Natural
  • Affordable

Mental Wellness Backed by Science

Our L-Methylfolate + Methyl B12 formula was developed for people who want a simple, natural way to support mood, focus, emotional balance, and clear daily thinking without depending on stimulants or complicated supplement stacks.

L-Methylfolate (5-MTHF) is the bioactive form of folate that the body can actually use right away to support healthy neurotransmitter production. When combined with Methyl B12, it provides foundational support for mental clarity, calm mood, and steady daily energy.

Most folate products use cheaper forms that require conversion inside the body, and many people do not convert them efficiently. This formula delivers the active form directly, so you get meaningful support you can actually feel.

Instead of guessing which brain supplement might help, this gives you a clean, highly absorbable foundation for cognitive wellness. It fits easily into your day and makes it simple to feel more focused, more emotionally regulated, and more mentally clear.

PureRoot Labs L-Methylfolate
Excellent 4.8 | 2,839 reviews

PureRoot Labs L-Methylfolate

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Frequently Asked Questions

Will I actually feel a difference? +

Most customers report feeling more mentally clear, steady, and calm within a few weeks of consistent daily use. Results vary person to person, but many notice subtle improvements sooner.

What makes this different from regular folate or B12? +

We use the active forms (5-MTHF + Methyl B12) that the body can use right away. Most cheaper folate forms require conversion first.

Can this help with focus + daily attention? +

This formula supports healthy neurotransmitter balance, which plays a key role in mental clarity and maintaining attention throughout the day.

Is it safe to take daily + long term? +

Yes. These are nutrients the body naturally relies on. This formula is designed for daily support when used as directed.

Can I take it with my other vitamins or supplements? +

In most cases, yes. Many people take this alongside their normal supplement routine. If you’re on medication or have a condition, speak with your healthcare provider first.

Will this help with mood support? +

It is formulated to support emotional balance and calm, which many customers take specifically for mood-related wellness.

How long before full results? +

Most users experience more noticeable support within 6–8 weeks as nutrient levels become more stable with consistent daily use.

How fast is shipping? +

All orders are inspected to ensure quality for our customers.

Orders are typically processed within 1–3 business days and delivered within 5–10 business days, depending on your location.

PureRoot Labs is based in the USA, and to cut down on Carbon Emissions, we send our products from all around the world, including Europe, Oceania/Asia, and the United States.

🌱 We’re committed to reducing our environmental impact — whenever possible, we consolidate shipments to minimize carbon emissions.

What makes this different from regular folate or B12? +

We use the active forms (5-MTHF + Methyl B12) that the body can use right away. Most cheaper folate forms require conversion first.

Is it safe to take daily + long term? +

Yes. These are nutrients the body naturally relies on. This formula is designed for daily support when used as directed.

Will this help with mood support? +

It is formulated to support emotional balance and calm, which many customers take specifically for mood-related wellness.

How fast is shipping? +

All orders are inspected to ensure quality for our customers.

Orders are typically processed within 1–3 business days and delivered within 5–10 business days, depending on your location.

PureRoot Labs is based in the USA, and to cut down on Carbon Emissions, we send our products from all around the world, including Europe, Oceania/Asia, and the United States.

🌱 We’re committed to reducing our environmental impact — whenever possible, we consolidate shipments to minimize carbon emissions.